Contact Information
Directions to our Institute
Public Health Research Institute
New Jersey Medical School - University of Medicine and Dentistry of New Jersey
Department of Molecular Genetics, Third floor - West Wing
225 Warren Street
Newark, New Jersey 07103
| Fred Russell Kramer, Ph.D. | Sanjay Tyagi, Ph.D. | Salvatore A.E. Marras, Ph.D. |
| Room W-310A | Room W-310E | Room W-350A |
| Tel: 1-973-854-3370 | Tel: 1-973-854-3372 | Tel: 1-973-854-3373 |
| fred.kramer@umdnj.edu | tyagisa@umdnj.edu | marrassa@umdnj.edu |
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Recent Publications from Our Group
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In the November 23, 2011 issue of Cell, using our unique single-molecule imaging approach, we describe circumstances under which splicing is uncoupled from transcription. An interview conducted by Cell's editorial staff with Sanjay Tyagi about this work can be listened to at www.cell.com/../paperclip.mp3 |
Vargas DY, Shah K, Batish M, Levandoski M, Sinha S, Marras SAE, Schedl P, Tyagi S (2011) Single-molecule imaging of transcriptionally coupled and uncoupled splicing Cell 147, 1054-1065.
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We describe a protocol for a novel method that utilizes single labeled Fluorescent In-situ Hybridization probes to image individual mRNA molecules |
Batish M, Raj A, and Tyagi S (2011) Single Molecule Imaging of RNA In Situ. Methods in Molecular Biology 714, 3-11.
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In collaboration with Diana Bratu and Irina Catrina at Hunter College in New York City, we published on the design parameters and applications of Locked Nucleic Acid (LNA) based molecular beacon probes to detect RNA in live cells |
Bratu DP, Catrina IE, and Marras SAE (2011) Tiny molecular beacons for in vivo mRNA detection. Methods in Molecular Biology 714, 141-157.