molecular beacons


Recent Publications from Our Group

In collaboration with Lieve Naesens at KU Leuven, Belgium, we developed a molecular beacon-based high-throughput screening assay to compare the activity of potential endonuclease inhibitors.

Stevaert A, Nurra S, Pala N, Carcelli M, Rogolino D, Shepard C, Domaoal RA, Kim B, Alfonso-Prieto M, Marras SAE, Sechi M, and Naesens L (2015) An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease. Molecular Pharmacology 87, 323-337.

In collaboration with Nikhat Parveen at New Jersey Medical School, we developed a multiplex real-time PCR assay for the detection of tick-born pathoges B. burgdorferi, B. microti and A. phagocytophilum.

Chan K, Marras SAE, and Parveen N (2013) Sensitive multiplex PCR assay to differentiate Lyme spirochetes and emerging pathogens Anaplasma phagocytophilum and Babesia microti. BMC Microbiology 13, 295.